A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma


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Oct. 18, 2021, 7:46 a.m.

A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma

Piqué, D.G., Montagna, C., Greally, J.M. et al.
Piqué, D.G., Montagna, C., Greally, J.M. et al. A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma. Br J Cancer 120, 746–753 (2019). https://doi.org/10.1038/s41416-019-0387-8
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  Mean reproducibility score:   4.0/10   |   Number of reviews:   1

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Why should we reproduce your paper?
This paper provides a novel approach to identifying oncogenes based on RNA overexpression in subsets of tumor relative to adjacent normal tissue. Showing that this study can be reproduced would aid other researchers who are attempting to identify oncogenes in other cancer types using the same methodology.
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Resources

  Paper URL: https://www.nature.com/articles/s41416-019-0387-8
  Data URL: https://portal.gdc.cancer.gov/projects/TCGA-BRCA
  Code URL: https://static-content.springer.com/esm/art%3A10.1038%2Fs41416-019-0387-8/MediaObjects/41416_2019_387_MOESM2_ESM.html
Tags: R

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